ea0009p66 | Growth and development | BES2005
Joseph F
, Chan B
, Corlett P
, Durham B
, Ahmad A
, White H
, Wherley N
, Vinjamuri S
, Gallagher J
, Fraser W
, Vora J
BACKGROUD: Parathyroid hormone (PTH) is normally secreted in a circadian rhythm and modulates bone turnover through the differential stimulation of receptor activator for nuclear factor kappa-B ligand (RANKL) and suppression of osteoprotegerin (OPG), both of which are fundamental factors in regulating bone turnover. We have studied the relationship between PTH and OPG over a 24-hour period.METHODS: Hourly peripheral venous blood samples were obtained fro...